JLS and Tinie Tempah win 2 MOBO Awards each
The X Factor 2008 runners-up were named Best UK Act and took home the Best Album prize.
JLS also performed with Travie McCoy on his hit single Billionaire during the ceremony.
Tinie Tempah won Best Newcomer and Best Video for Frisky.
'Last year I was here as a spectator just watching my friends pick up awards,' he said.
'So now it's nice to be here and to have
finally won something.'
Other winners included Eminem for Best International Act, Plan B was Best UK R&B And Soul Act and Professor Green was Best UK Hip Hop And Grime Act.
N-Dubz were awarded the Best Song trophy for Playing With Fire, while Billy Ocean received the Lifetime Achievement gong.
Full winners for MOBO Awards 2010:
Best Newcomer - Tinie Tempah
Best UK R&B And Soul Act - Plan B
Best UK Hip Hop And Grime Act - Professor Green
Best International Act - Eminem
Best Reggae Act - Gyptian
Best Album - JLS
Best Video in association with MTV Base - Tinie Tempah ft Labrinth - Frisky
Best UK Act in association with Lebara Mobile - JLS
Best Song in association with PRSforMusic - NDubz FEAT. Mr Hudson - Playing with Fire
Best African Act - K'Naan
Best Jazz Act - Empirical
Best Gospel Act - Guvna BLifetime Achievement - Billy Ocean
BeMOBO - Merseyside Dance Initiative